Overview
A water-soluble peptide composed of 43 amino acids, a naturally occurring endogenous repair peptide in the human body. Isolated from calf thymus in 1966, it is involved in cytoskeleton regulation, tissue remodeling and inflammation balance.
| Chemical Class | Thymosin beta 4 polypeptide |
| Dosage Form | Lyophilized powder |
| Specification | 2mg/5mg/10mg |
| Storage | Lyophilized at -20°C / reconstituted at 2-8°C |
Mechanism of Action
Actin regulation: LKKTET motif binds G-actin to maintain cell motility
Cell migration and angiogenesis: Integrin/VEGF/PI3K pathway promotes tissue remodeling
Inflammation regulation: NF-κB inhibition + NLRP3 inflammasome downregulation
Fibrosis restriction: ILK → GSK3β → GLI2 signaling downregulation
Related to indications: Multiple pathways work together to support tissue repair and inflammation balance.
| Indication | Mechanism | Evidence |
|---|
| Repair support after tissue damage | Cell migration + actin regulation | experimental research |
| Sports related soft tissue recovery | Inflammation regulation + tissue remodeling | experimental research |
| Assisted regulation of chronic inflammatory conditions | NF-κB/NLRP3 inhibition | experimental research |
| Postoperative/post-trauma recovery support | Angiogenesis + epithelial regeneration | experimental research |
| Maintenance of fibrosis-prone tissues | Hedgehog/ILK pathway regulation | experimental research |
Dosage & Administration
Safety Information
Regulatory Status
Explanation of missing informationLack of clear regulatory status information. It is recommended to check the FDA Orange Book, NMPA Drug Evaluation Center, and WADA banned list.
Drug Interactions
FAQ
Q1: How long will it take to see changes?
The change time varies greatly depending on the product mechanism and personal physique. It is recommended to refer to clinical trial data of similar products.
Q2: Will it rebound after deactivation?
Depends on product category and individual maintenance regimen. Metabolic products may gradually return to baseline; repair products are usually long-lasting.
Q3: Can it be used with other supplements?
In most cases, it is possible, but care should be taken to avoid overlapping products with the same mechanism. Please refer to Module 13 ‘Drug Interactions’ for details.
Q4: Why is it banned for athletes?
Some products are included in WADA’s banned list. Athletes should check the latest WADA list before use.
Q5: What is the difference from XX products?
Please see the competitor comparison matrix for this category.
Q6: Are there any side effects?
Please see Module 12 ‘Safety and Toxicology Details’.
Q7: Does it need to be used for a long time?
Depends on product category and target. Please refer to Module 10 ‘Dosage and Administration’ for treatment recommendations.
Q8: Who is not suitable?
Please refer to Module 8 ‘Contraindications and Precautions’.with precautions’.| — | — |Zero tolerance statement for literature: The above reference list is exclusive and unique to this SKU. Each citation must be verified by PubMed/ClinicalTrials before being filled in. Unverified literature is prohibited from being used in the main text description. An overall literature summary table across products does not exist in the manual.
Disclaimer: This product is intended for research purposes only. Not for human consumption or therapeutic use. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
